Research Articles
Dissecting the Tumor Immune Microenvironment with Single-Cell RNA Sequencing: From Cellular Heterogeneity to Clinical Translation
Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of the tumor immune microenvironment (TIME) by enabling unprecedented resolution of cellular heterogeneity, functional states, and intercellular communication networks.
Decoding Cancer Stem Cells: A Single-Cell Sequencing Guide for Identification and Therapeutic Targeting
This article provides a comprehensive overview of how single-cell sequencing (SCS) technologies are revolutionizing the identification and characterization of cancer stem cells (CSCs).
Decoding the Tumor Microenvironment: A Single-Cell Atlas for Discovery and Therapeutic Innovation
Single-cell atlases are revolutionizing our understanding of the tumor microenvironment (TME), providing unprecedented resolution of its cellular composition, heterogeneity, and communication networks.
Decoding Cancer Evolution: Single-Cell Analysis of Clonal Dynamics and Therapeutic Resistance
This article provides a comprehensive overview of how single-cell technologies are revolutionizing our understanding of clonal evolution in cancer.
Circulating Tumor Cells: Decoding Their Critical Role in Cancer Metastasis for Research and Therapeutic Development
This article comprehensively examines the multifaceted role of Circulating Tumor Cells (CTCs) in cancer metastasis, providing a resource for researchers, scientists, and drug development professionals.
Dissecting Tumor Heterogeneity: A Single-Cell Sequencing Guide for Cancer Research and Drug Development
Single-cell sequencing technologies have revolutionized our understanding of tumor heterogeneity, providing unprecedented resolution to analyze the complex cellular ecosystems of cancer.
ddPCR vs BEAMing: A Strategic Guide for Mutation Detection in Research and Diagnostics
This article provides a comprehensive comparison of Droplet Digital PCR (ddPCR) and BEAMing (Beads, Emulsion, Amplification, and Magnetics) for the detection of genetic mutations.
Mastering Limit of Detection in ddPCR: A Comprehensive Guide for Robust Assay Development
Droplet Digital PCR (ddPCR) enables ultrasensitive nucleic acid detection and absolute quantification, making precise Limit of Detection (LoD) studies crucial for applications from rare mutation detection to pathogen surveillance.
Analytical Validation of ctDNA Tests: Advances, Methods, and Clinical Implementation for Precision Oncology
This article provides a comprehensive overview of the analytical validation of circulating tumor DNA (ctDNA) tests, a cornerstone of precision oncology.
Digital PCR Platforms Compared: A 2025 Guide for Researchers and Drug Developers
This article provides a comprehensive comparison of digital PCR (dPCR) platforms for researchers, scientists, and drug development professionals.