Research Articles
Blood Collection Tubes for Liquid Biopsy: A Comprehensive Guide for Research and Drug Development
This article provides a detailed examination of specialized blood collection tubes, a critical pre-analytical component in liquid biopsy workflows for researchers and drug development professionals.
Optimizing ddPCR for ctDNA Detection: A Comprehensive Protocol Guide for Cancer Researchers
This article provides a detailed guide for researchers and drug development professionals on implementing and optimizing droplet digital PCR (ddPCR) for circulating tumor DNA (ctDNA) detection.
ctDNA as a Prognostic Biomarker: From Foundational Principles to Clinical Validation in Precision Oncology
Circulating tumor DNA (ctDNA) has emerged as a transformative, non-invasive biomarker in oncology, offering real-time insights into tumor dynamics.
Minimal Residual Disease (MRD) Detection: A Comprehensive Guide to Technologies, Clinical Applications, and Future Directions
This article provides a comprehensive overview of Minimal Residual Disease (MRD) detection, a pivotal biomarker for assessing relapse risk and guiding treatment in hematological malignancies and solid tumors.
Digital PCR for Absolute Quantification: A Comprehensive Guide for Biomedical Research and Clinical Diagnostics
Digital PCR (dPCR) represents a transformative advancement in nucleic acid quantification, enabling calibration-free absolute measurement of target sequences.
Droplet Digital PCR: A Comprehensive Guide to Principles, Workflow, and Cutting-Edge Applications
This article provides a detailed exploration of Droplet Digital PCR (ddPCR), a third-generation PCR technology renowned for its absolute quantification of nucleic acids without the need for standard curves.
Cell-Free DNA vs Circulating Tumor DNA: A Comprehensive Guide for Cancer Researchers and Drug Developers
This article provides a detailed comparative analysis of cell-free DNA (cfDNA) and circulating tumor DNA (ctDNA) for an audience of researchers, scientists, and drug development professionals.
ctDNA Clearance Dynamics: From Half-Life Fundamentals to Clinical Trial Applications
This article provides a comprehensive examination of circulating tumor DNA (ctDNA) half-life and clearance dynamics, tailored for researchers and drug development professionals.
Liquid Biopsy in Oncology: A Comprehensive Review of Clinical Applications, Technical Advances, and Future Directions
This article provides a comprehensive analysis of liquid biopsy's transformative role in oncology, tailored for researchers and drug development professionals.
ddPCR for Rare Mutation Detection: A Comprehensive Guide for Precision Oncology and Biomarker Research
Droplet Digital PCR (ddPCR) has emerged as a powerful technology for the precise detection and absolute quantification of rare mutations, revolutionizing applications in liquid biopsies, cancer monitoring, and disease research.